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From Hyperthermia to Thermotherapy

In the video from MyWave COST Action, you can see how electromagnetic waves or radiofrequency waves cause heating of tissue. Mild elevation (up to 43 degrees C) is known as hyperthermia. It changes the micro-environment of the tumor and makes it more sensitive to radio- and chemotherapy. This is proven in many Phase III patient studies (see scientific background). Higher temperatures destroy cells, this is known as ablation.

Hyperthermia has not been widely adopted because of poor performance of existing solutions, low usability and lack of economics. By reinventing the heating technology, Sensius changes the paradigm on hyperthermia:

  • Unmatched performance through focus of the heat to the tumor and protection of nearby sensitive organs. Physicians have full control over the treatment through image guided treatment planning and adaptive delivery.
  • Optimal usability through full alignment with the radiotherapy workflow to reduce the learning curve, preservation of a single patient record and combination of radio- and thermo- treatment plans.
  • Outstanding economics by an attractive pricing model.

This is how Sensius changes hyperthermia into thermotherapy.

Thermotherapy for Head and Neck

Sensius offers a complete solution to administer deep thermotherapy for the head and neck region. The solution is based on the Hypercollar3D technology from Erasmus Medical Center Cancer Center. Development started more than 10 years ago and several dozens of patients have been treated with the Hypercollar and the Hypercollar3D.

A key element in the design of the HyperCollar3D is to control SAR in virtually all regions of the full head & neck area. Organs at risk like the spinal cord, eyes and other areas can be properly protected against hotspots through its smart placement and control of antenna power. The Hypercollar3D solution treatment is fully supported by software planning and control during treatment delivery. This level of planning enables the radiation-oncologist to set specific treatment objectives and minimize undesired side effects. During treatment, near-realtime adaptation of the plan is possible based on measurements and patient feedback. Treatment interruption is minimized. The horseshoe shape of the applicator ensures patient comfort and facilitates patient setup and easy evacuation after treatment.

The HyperCollar3D comes with full software support. Valerio Fortunati, winner of the STW “Simon Stevin gezel” award 2016 explains: “Using the tool improves the clinical routine: not only by speeding up the process of modelling, but also by having a more precise and more consistent model over all patients”. Thanks to the supporting software, treatment is reliable and reproducible. Physicians can accurately control dose and will be confident about the way the patient will be treated.

(video courtesy of STW the Netherlands)

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